Hypotheon Mission Badge

Hypotheon — The Engine of Insight

Agentic AI for biological discovery — connecting scientific grounding with scalable inference.

Systematically exploring and exhausting the hypothesis space around a biological target — revealing what’s validated, what’s emerging, and what remains unexplored.

// Step 01 — Ask | Expand | Organize

Transforms focused seed questions into structured, mechanistically organized hypotheses through scalable inference and clustering. Unbiased. Scalable. Structured.

Seed to Hypothesis Clusters
// Step 02 — Extract | Map | Compare

Extracts key biological entities from each hypothesis. Builds a mathematical co-occurrence map and compares it with an LLM-inferred network, surfacing asymmetric, cross-domain insights. Precise. Comparative. Insight-Driven.

Step 02 - Extract Map Compare Diagram
// Step 03 — Ground | Rank | Reveal

Links inferred networks to omics, literature, and clinical data — distinguishing what’s validated, what’s emerging, and what’s unexplored.

Validated, Emerging, Unexplored

Transforms scattered hypotheses into ranked mechanistic landscapes.

// Example — The Neuropeptide Galanin

From ~30 structured hypotheses, Hypotheon extracted nearly 700 biological entities, mapping relationships that reveal new pathways, biomarkers, and therapeutic opportunities.

Galanin Network Visualization
// Step 04 — Act | Design | Translate — Hypotheon Labs

Translates discovery into action:
• Proposes grounded experiments from inferred mechanisms
• Prioritizes models and readouts by feasibility and cost
• Builds CRO-ready blueprints for rapid validation

Hypotheon Labs Schematic

🚧 Under Construction 🚧

We’re building out this section — including a GitHub repo, entity network demos, and additional visual workflows.

Check back soon for updates.

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